Polycythaemia vera and Christmas disease with slightly prolonged prothrombin time.
نویسنده
چکیده
A family is reported in which Christmas disease in one member and polycythaemia in another were associated with prolongations of the one-stage prothrombin time of the factor-VII deficiency type. Changes in the prothrombin time were present in the siblings of the case of Christmas disease and in a number of unrelated cases of polycythaemia vera. The use of "mixing procedures" did not reveal any significant mutual correction of the changes in prothrombin time.
منابع مشابه
An investigation of three patients with Christmas disease due to an abnormal type of factor IX.
Three patients with Christmas disease whose plasma was shown to have a prolonged one-stage prothrombin time with ox brain thromboplastin have been investigated. These patients have an inhibitor for the reaction between factor X, factor VII, and ox brain extract. The abnormal constituent responsible for this inhibitor appears to be factor IX whuch is functionally inactive but antigenically indis...
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عنوان ژورنال:
- Journal of clinical pathology
دوره 13 شماره
صفحات -
تاریخ انتشار 1960